| What is PPH? |
| (PPH) is a rare and, as yet, incurable disease. It is a rare blood vessel disorder of the lung in which the pressure in the pulmonary artery (the blood vessel that leads from the heart to the lungs) rises above normal levels and may become life threatening. PPH is extremely rare, occurring in about two persons per million population per year. |
| Symptoms |
| Typical symptoms of Pulmonary Hypertension can include shortness of breath with minimal exertion, fatigue, chest pain, dizzy spells, swelling in the ankles or legs, bluish lips and skin, racing pulse or palpitations, and fainting. |
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Cypher Stent |
On October 30, 2003, the FDA released an advisory about adverse events associated with Cordis Corp.'s Cypher Coronary Stent. The stent is a cylindrical metal mesh used in patients undergoing angioplasty. It works by opening clogged coronary arteries. While many patients have been treated with the Cypher stent without complications, the FDA has increasingly received reports of thrombosis, or clotting. There are now more than 290 reports of thrombosis. Typical complications start within a one to thirty day period following the procedure during which the device is implanted. In more than sixty of the reports received by the FDA, the patients suffered death associated with the stent. The other cases involved injury and medical and/or surgical intervention. The FDA has also received more than 50 reports (including some deaths) that involve hypersensitivity reactions. The symptoms include: pain, rash, respiratory alterations, hives, itching, fever, and blood pressure changes. The cause of these adverse events has not yet been determined.
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